Welcome to this UK AstraZeneca produced and funded website

This website is intended for UK Healthcare Professionals only.

 

The website contains both promotional and non-promotional content.

 

If you are a patient or a carer of a patient prescribed an AstraZeneca product, please visit myazmed.co.uk

 

For any other UK residents please visit astrazeneca.co.uk

I am not a Healthcare Professional
Prescribing Information FLUENZ® nasal spray suspension (influenza vaccine, live attenuated, nasal)
Adverse Event Reporting

This website is intended for UK Healthcare Professionals only. Other UK residents please visit astrazeneca.co.uk

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FAQs & Training

 

FAQs & Training

Refresh your knowledge of administering the nasal spray flu vaccine and discover effective approaches for engaging in conversations with parents. Access a full range of resources, including step-by-step administration videos, FAQs, and real-world nurse case studies.

  • Licensed Indication
  • Administration
  • FAQs + MI
  • Educating Parents and Children
  • Supporting your conversations with parents

How to administer Fluenz

Fluenz is administered as a nasal spray; it must not be injected.

Click through the carousel below for a clear, step-by-step guide on how to administer the Fluenz nasal spray flu vaccine.

Step 1a | Before the Vaccine is administered, check vaccine1

 

Check the appearance.

This can vary, but should fit the following description: 
colourless to pale yellow, clear to opalescent suspension, with or without small white particles. Do not use Fluenz if the sprayer appears damaged, for example, if the plunger is loose or displaced from the sprayer or if there are any signs of leakage. 

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Step 1b | Before the Vaccine is administered, check vaccine1

 

Check the expiry date.

Please remember Fluenz has a maximum shelf life of 15 weeks. Always check the expiry date (day, month, year) on individual sprayers before administration and the vaccine can be administered up to and including on the day of expiry.Before use, the vaccine may be taken out of the refrigerator once for a maximum period of 12 hours at a temperature not above 25°C.

Discard any unused vaccine at the end of the vaccination season to prevent use of expired vaccine in the future. In order to improve the traceability of biological medicinal products, the name and the batch number of the

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Step 2 | Prepare the applicator1

 

Prepare the applicator.

Prepare the applicator by removing the nozzle tip protector.
Do not remove the dose-divider clip at the other end of the applicator.This splits the 0.2 ml dose so that an equal 0.1 ml quantity can be delivered to each nostril

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Step 3 | Postion the applicator1

 

Position the applicator.

With the recipient in an upright position, place the tip just
inside the first nostril, to ensure vaccine is delivered into the nose.

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Step 4 | Depress the plunger1

 

Depress the plunger

With a single motion, depress the plunger as quickly as
possible until the dose-divider clip stops it going any further. The recipient can breathe normally when they are receiving vaccine, they do not have to actively inhale or sniff.
Please note: the vaccine does not need to be re-administered if the patient sneezes, or blows their nose following administration.2

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Step 5 | Remove the dose-divider clip1

 

Remove the dose-divider clip.

To administer the vaccine to the second nostril, pinch the dose-divider clip to remove it from the applicator.

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Step 6 | Spray in the nostri1

 

Spray in the other nostril

Place the tip just inside the second nostril and, with a single motion, depress the plunger as quickly as possible to deliver the remaining dose. Make sure any used product or waste material is disposed of in accordance with local requirements for medical waste

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Needle fear is a common barrier to vaccination that affects 5-13% of children, with 45% of 4 to 6-year-olds showing distress during routine injections3-5. Fluenz is a nasal spray flu vaccine that provides flu protection without the need for injection1.

 

Watch the video below for guidance on how to administer the Fluenz nasal spray flu vaccine to children:

Discover expert insights in the videos below, where Pauline Macdonald addresses key questions about Fluenz and Nimisha Vinod explores how motivational interviewing can support conversations around vaccine hesitancy.

 

Use the timestamps to navigate directly to the sections most relevant to you and access practical insights throughout.

Frequently Asked Questions

Hear Pauline Macdonald (Independent Consultant and former member of the JCVI) address commonly asked questions surrounding Fluenz, including:

 

  1. Direct and indirect benefits of vaccination with LAIV for children and parents (04:42)
  2. How to use the Nasal Spray Flu Vaccine (05:38)
  3. Guidance from religious bodies on the use of gelatine in vaccines (12:20)
  4. How to administer the Nasal Spray Flu Vaccine and post-administration advice (16:28)
  5. How to order and when to request additional supply (21:20)
  6. Where to find support (for both children and parents) (22:40)

This was a promotional event for pharmacists.

Play now

24:14 (mins)

Motivational Interviewing

Listen to Nimisha Vinod (Improvement Advisor, AQUA) discuss how to overcome vaccine hesitancy in a presentation focused on 'motivational interviewing'. Key topics discussed include:

 

  1. What is motivational interviewing? (01:08)
  2. The four guiding principles (02:55)
  3. The importance of ambivalence (05:25)
  4. Core skills of motivational interviewing O.A.R.S (10:00)
  5. Ask-Share-Ask framework (19:20)
  6. The different stages of motivational interviewing (20:49)

 

 

 

 

Play now

24:14 (mins)
 

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Educating Parents and Children

For Younger Children

For Older Children

For Parents

Hear from Vaccination & Immunisation Nurse, Valarie, as she takes us through the following:

 

  1. What is flu?
  2. Why the flu vaccination is important
  3. What happens on vaccination day

These videos are designed to be downloaded and used by local teams to help educate parents and children ahead of their immunisation appointments. Each video has been carefully tailored to suit the language needs and developmental understanding of parents and children across different age groups, ensuring clear, accessible, and age-appropriate communication.

 

Follow the steps below for optimal delivery.

Step 1 | Download the video that best matches the age group receiving the immunisation here.

 

Step 2 | Add the video to your chosen PowerPoint template and update with your local team's information. Find your PowerPoint template here.

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Supporting your conversations with parents

Share Good Times, Not Flu is a parent-friendly website developed by AstraZeneca is designed to address common questions and concerns, while highlighting why flu vaccination matters and explaining key information about the flu vaccine in clear, accessible language.

Helping You Drive Consent

To further support your vaccination programme, we’ve created a dedicated page to help promote completion of local consent forms within your area.


If you would like your local consent form featured on this page, please email AZexchangeUK@astrazeneca.com with:

 

  • The local area(s) you cover 
  • A direct link to your consent form 
  • Confirmation you are happy for us to host the link for your areas

 

We’ll ensure your information is added to help make the consent process as simple and visible as possible for parents.

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Fluenz is indicated for active immunisation for the prevention of influenza disease in children and adolescents from 2 years to less than 18 years of age. Fluenz should be used in accordance with official recommendations.1

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  1. Fluenz nasal spray suspension Influenza vaccine (live attenuated, nasal) Summary of Product Characteristics. Accessed: April 2026.
Available at: https://www.medicines.org.uk/emc/product/15790/smpc 
  2. Department of Health. Immunisation Against Infectious Disease. (The Green Book.) Chapter 19: Influenza. London: The Stationery Office. Nov 2023. Accessed: March 2026. Available at: Green book chapter 19 Influenza (publishing.service.gov.uk). 
  3. McLennon J, Rogers MA. J Adv Nurs. 2019 Jan; 75(1): 30-42.
  4. Taddio A, et al. Vaccine. 2022; 40(52): 7526-7537. 
  5. McMurtry MC, et al. Clin J Pain. 2015; 31(Suppl 10): S3-S11.

GB-75345 | July 2026

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to AstraZeneca by visiting https://contactazmedical.astrazeneca.com/ or by calling ‌‌‌0‌‌‌8‌‌‌‌‌0‌‌‌‌0‌‌‌ ‌‌7‌‌‌‌‌‌8‌‌‌3‌‌‌ ‌‌0‌‌‌‌‌0‌‌‌‌3‌‌‌‌3‌‌‌.

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This website was created for UK HCPs and has been designed to provide information to educate, empower and enable them in the great work they are doing for patients across a range of therapy areas. This website is intended for doctors, nurses, and pharmacists in the UK. Other UK residents please visit astrazeneca.co.uk.

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