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IMFINZI (durvalumab) UK Prescribing Information
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Resources

A New Era in MIBC Care

NOW APPROVED in the UK: The IMFINZI NIAGARA regimen* – the FIRST and ONLY perioperative IO regimen approved in the UK for your cisplatin-eligible, resectable MIBC patients1,2

Indication: IMFINZI in combination with gemcitabine and cisplatin as neoadjuvant treatment, followed by IMFINZI as monotherapy adjuvant treatment after radical cystectomy, is indicated for the treatment of adults with resectable MIBC1

Resources:

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Improving MIBC Management in

the UK & MDT Best Practice

Hear from Prof. James Catto, NIAGARA trial investigator, on the evolving management of MIBC in the UK and his insights into MDT best practice. 

FIND OUT MORE

GB-71694 | November 2025

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NIAGARA Trial Data Overview
with Prof. Tom Powles

In this short video, NIAGARA principal investigator Prof. Tom Powles discusses the key efficacy and safety findings from the NIAGARA trial, along with practical considerations for the treatment and management of MIBC.

FIND OUT MORE

GB-71695 | November 2025

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Dosing and
Administration Guide

A guide to support dosing and administration of the perioperative IMFINZI NIAGARA regimen* in eligible MIBC patients.

VIEW ONLINE

GB-71165 | October 2025

All materials for healthcare professionals are intended to be viewed online. Contact us below if you would like us to request a printed copy.

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NIAGARA Trial
Summary Booklet

A booklet summarising key efficacy and safety data from the NIAGARA trial.

VIEW ONLINE

GB-71697 | November 2025

All materials for healthcare professionals are intended to be viewed online. Contact us below if you would like us to request a printed copy.

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NIAGARA
Patient Brochure

A supportive booklet designed to guide patients through their MIBC diagnosis and treatment journey with IMFINZI (durvalumab)

VIEW ONLINE

GB-71696 | November 2025

For more information, or to request printed copies of the resources above, contact an AstraZeneca representative or sign up to our mailing list

Contact us or sign up to mailing list

*The perioperative IMFINZI NIAGARA regimen is defined as neoadjuvant IMFINZI + gem-cis followed by adjuvant IMFINZI as a single agent after RC1,2

MIBC, muscle-invasive bladder cancer; gem-cis, gemcitabine-cisplatin; RC, radical cystectomy; IO, immune-oncology. 

 

  1. IMFINZI, Summary of Product Characteristics.
  2. Powles T, et al. N Engl J Med. 2024;391(19):1773-1786 (including Supplementary Appendix and Protocol).

 

GB-71162 | October 2025

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to AstraZeneca by visiting https://contactazmedical.astrazeneca.com/ or by calling ‌‌‌0‌‌‌8‌‌‌‌‌0‌‌‌‌0‌‌‌ ‌‌7‌‌‌‌‌‌8‌‌‌3‌‌‌ ‌‌0‌‌‌‌‌0‌‌‌‌3‌‌‌‌3‌‌‌.

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