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Prescribing information WAINZUA®▼(eplontersen)
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This website is intended for UK Healthcare Professionals only. Other UK residents please visit astrazeneca.co.uk

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  • Resources | WAINZUA®▼(eplontersen) | AstraZeneca UK
  • Welcome to WAINZUA
  • About ATTR Amyloidosis
  • Why WAINZUA
    • Mechanism of Action
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WAINZUA®▼(eplontersen) Resources

WAINZUA resources

Discover resources about hereditary transthyretin-mediated amyloidosis with polyneuropathy (ATTRv-PN) and WAINZUA designed for both healthcare professionals and patients.

  1. HCP Resources
  2. Patient and Carer Resources
  3. Order Patient Materials

HCP resources

These resources have been developed and funded by AstraZeneca and contain mentions of AstraZeneca’s products.

Infographics

Acapella Patient Support Programme (PSP) infographic

Learn more about how your patients receiving WAINZUA can access additional support (including dietary support, counselling, physiotherapy and on-demand nurse care), via the Acapella PSP.

 

The Acapella PSP, initiated, managed, and funded by AstraZeneca UK, provides holistic support to help patients navigate their treatment and manage their condition. The service is free to the NHS and all patients receiving WAINZUA

Download

WAINZUA Homecare Service infographic

 

Learn more about the Homecare Service and what it offers, including nurse-led device training to support treatment flexibility for patients.

 

 

WAINZUA Homecare Service is available only to eligible patients at healthcare organisations that have formally signed up
to it

 

 

Download

Quality of life and disease burden infographic

 

Understand the true burden of ATTRv-PN and the impact of disease on patients and caregivers

 

 

 

 

 

 

 

 

 

Download

Videos

The Acapella Patient Support Programme

A video to explain what the Acapella Patient Support Programme is, and how it may benefit your patients following diagnosis with Stage 1 and 2 ATTRv-PN and the decision has been made to prescribe WAINZUA. The video explains the various resources and healthcare team support for patients.

 

Watch the video
Web

Dr Ahmad Masri: Experience with WAINZUA

 

 

 

Watch Dr Ahmad Masri describe his real-world experience with WAINZUA and how WAINZUA has impacted patient outcomes

 

 

Watch the video

Dr Ahmad Masri Case Study: Newly-diagnosed patient treated with WAINZUA

 

Watch Dr Ahmad Masri describe a case study of a newly-diagnosed patient with mixed phenotype ATTR amyloidosis treated with WAINZUA

 

Watch the video

Dr Ahmad Masri Case Study: Mixed phenotype patient switched to WAINZUA

Watch Dr Ahmad Masri describe a case study of a patient with mixed phenotype ATTR amyloidosis who switched treatment to WAINZUA

Watch the video

Prof. Marianna Fontana: The effect of WAINZUA on autonomic dysfunction and nutritional status

Watch Prof. Marianna Fontana describe the impact of WAINZUA on measures of autonomic function and nutritional decline in the Neuro-TTRansform study

Watch the video
Web

Dr Ahmad Masri: Management approaches for ATTR amyloidosis

Watch Dr Ahmad Masri highlight challenges faced by patients with ATTR amyloidosis and how personalised care can improve patient outcomes

Watch the video

Prof. Julian Gillmore: Recognising red flags and the impact of autonomic neuropathy on quality of life

Watch Prof. Julian Gillmore explain the challenges of diagnosing ATTR amyloidosis and the importance of clinical vigilance for identifying polyneuropathy symptoms

 

 

 

Watch the video

Prof. Marianna Fontana: WAINZUA’s self-administration, Homecare, and Patient Support

Watch Prof. Marianna Fontana highlight the elements of WAINZUA’s flexible and supportive services available to patients. WAINZUA Homecare Service is available
only to eligible patients at healthcare organisations that have formally signed up to it.

Watch the video

Patient and Carer Resources

Disease information booklet

 

Everything patients need to know about ATTRv-PN

 

Download

WAINZUA patient 
 information booklet

Everything patients need to know about WAINZUA, including a personal injection 
and appointment tracker

Download

WAINZUA instructions 
for use booklet

Step-by-step guidance on how to administer WAINZUA

 

Download

Patient support websites

Connecting with the National Amyloidosis Centre (NAC), patient organisations and charities about ATTRv-PN can:

  • Provide further information and support
  • Help your patients understand how they can get involved in their own care
  • Support your patients in connecting with others who have similar experiences

National Amyloidosis Centre

 

Carers UK

The Patients Association

 

Amyloidosis UK

Order Patient Materials

If you wish to order hard copy materials, please submit the form below:


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Disease education

 

See the pATTRns website

 

The 'See the pATTRns' website is an educational resource for UK healthcare professionals. Visit to learn about ATTR amyloidosis pathophysiology, signs and symptoms, diagnostic algorithms and management approaches.

 

By clicking on the link below, you will be redirected to another AstraZeneca owned and funded website.

 

 

Go to site

 

 

Contact us

If you have any questions about WAINZUA or would like to speak to an AstraZeneca representative, please contact us.

Contact options

ATTR=transthyretin amyloidosis; ATTRv-PN=hereditary transthyretin amyloidosis with polyneuropathy; NHS=National Health Service; PSP=Patient Support Programme.

GB-62850 | November 2025

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to AstraZeneca by visiting https://contactazmedical.astrazeneca.com/ or by calling ‌‌‌0‌‌‌8‌‌‌‌‌0‌‌‌‌0‌‌‌ ‌‌7‌‌‌‌‌‌8‌‌‌3‌‌‌ ‌‌0‌‌‌‌‌0‌‌‌‌3‌‌‌‌3‌‌‌.

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This website was created for UK HCPs and has been designed to provide information to educate, empower and enable them in the great work they are doing for patients across a range of therapy areas. This website is intended for doctors, nurses, and pharmacists in the UK. Other UK residents please visit astrazeneca.co.uk.

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