Dosing and administration - FLAURA - Tagrisso (osimertinib)

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Dosing and
Administration: FLAURA

TAGRISSO is convenient for patients, with simple once-daily dosing.^1,2

TAGRISSO Dosage

The recommended dose is 80 mg once daily, with or without food.¹

TAGRISSO is available in a 40 mg and 80 mg tablet.^1,2

Image of a hand with two tablets above of 40mg and 80mg

One tablet,
once a day^1,2

Take with or
without food^1,2

In the comfort of
their home^1,2

TAGRISSO Administration

TAGRISSO should be swallowed whole with water and it should not be crushed, split or chewed.^1,2

Image of a glass that is half filled with water

For patients who have difficulty swallowing solids:^1,2

Disperse tablet in 50 ml of non-carbonated water only without crushing. Stir until tablet is dispersed into small pieces (the tablet will not completely dissolve), and swallow immediately. An additional half a glass of water should be added to ensure that no residue remains and then immediately swallowed. No other liquids should be added
TAGRISSO can be dissolved in water and swallowed or taken through an nasogastric (NG) tube. For administration via NG tube, please see the complete product labelling

Some situations may require dose interruption, discontinuation, or adjustment.^1,2 For information about dose modifications, please see the complete product labelling. If a dose modification is required, a 40 mg formulation is available.

In advanced disease, treat patients until disease recurrence or unacceptable toxicity.^1,2

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TAGRISSO (osimertinib) 40 mg Summary of Product Characteristics.
TAGRISSO (osimertinib) 80 mg Summary of Product Characteristics.

GB-63990 | DOP: July 2025

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Dosing and Administration: FLAURA

TAGRISSO Dosage

The recommended dose is 80 mg once daily, with or without food.1

One tablet,once a day1,2

Take with orwithout food1,2

In the comfort oftheir home1,2

TAGRISSO Administration

TAGRISSO should be swallowed whole with water and it should not be crushed, split or chewed.1,2

If a dose of TAGRISSO is missed, the dose should be made up unless the next dose is due within 12 hours1,2

Dosage Modification